This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.
Beilstein J. Org. Chem. 2019, 15, 2864–2871, doi:10.3762/bjoc.15.280
Graphical Abstract
Figure 1: Hydantoin-based commercially available drugs.
Scheme 1: Pseudothiohydantoin–thiohydantoin rearrangement.
Scheme 2: Syntheses of regioisomeric 5-spiro-substituted thiohydantoins and pseudothiohydantoins: previous [10] a...
Figure 2: Electrophilic centers of FPDs 1, starting materials of this study.
Scheme 3: Cyclocondensation of FPDs 1 with 1,3-binucleophilic reagents, resulting in pyrrole-2-one-bearing sp...
Scheme 4: Reaction of FPD 1a with thiourea.
Scheme 5: PTR of 3a to 2a.
Scheme 6: Pathways for the formation of compound 2a.
Scheme 7: Reaction of FPD 1a with monosubstituted thioureas.
Scheme 8: Reaction of FPDs 1 with 1,3-dibutylthiourea at room temperature.
Scheme 9: Plausible PTR pathways.
Beilstein J. Org. Chem. 2019, 15, 364–370, doi:10.3762/bjoc.15.32
Scheme 1: Approaches to the synthesis of the 5-azaisatin core.
Scheme 2: Our previous work on the interaction of PBTs 2 with thioamides.
Scheme 3: Interaction of PBTs 2 with thioacetamide.
Scheme 4: Plausible pathways for the formation of compound 4.
Scheme 5: Experiments on the intermolecular trapping of spiro[thiazolo-5,2'-pyrrole] 3a.
Scheme 6: Exploration of the substrate scope.
Scheme 7: Interaction of PBT 2a with N-phenylthioacetamide.